Scoville Splice  //  Cross-species capsaicinoid engineering

Beyond Peppers.

The Capsaicin Design Platform extends from Capsicum to 17 non-pepper organisms across 7 plant families. 57 named cultivar specifications — a spicy tomato, a spicy strawberry, a spicy rice.

57

Named products

17

Target organisms

7

Plant families

4

Engineering tiers

The thesis

Capsaicin is not a pepper problem.

The capsaicinoid biosynthesis pathway is a modular secondary metabolic system. The upstream phenylpropanoid branch (PAL → C4H → 4CL → HCT → COMT) is present in every vascular plant on Earth — it already feeds lignin, flavonoids, and other secondary metabolism.

Only 4 terminal pepper-specific enzymes — pAMT, Pun1/CS, KAS, BCAT — must be introduced into a target organism. The ESM2-engineered Pun1 variants, the FBA model, the blend optimizer, the construct assembly system: all transfer directly. The only new work per organism is codon re-optimization, tissue-specific promoter selection, and species-validated transformation protocols.

5 of 7 platform modules work unchanged for any organism. The platform is organism-independent at the protein level.

Four engineering tiers

Low-hanging fruit to the frontier.

T1

Low-Hanging Fruit

Solanaceae Core

  • 4-5 heterologous genes
  • 88-92% synteny with pepper
  • 18-24 months to first fruit
  • 5,000 — 1,000,000 SHU

Nightshade family shares a recent common ancestor with Capsicum. Tomato, eggplant, and tobacco carry the complete upstream phenylpropanoid pathway at high expression; only 4 terminal pepper-specific enzymes must be introduced.

T2

Achievable

Extended Nightshades & Physalis

  • 5-7 heterologous genes
  • 82-86% synteny
  • 24-36 months
  • 1,000 — 500,000 SHU

Still within the Solanaceae family or close relatives, but present additional challenges: tuber storage (potato), less-developed genomic resources (ground cherry, tomatillo), and ornamental use (petunia for floral tissue proof-of-concept).

T3

Hard

Cross-Family Engineering

  • 7-10 heterologous genes
  • cross-family
  • 36-48 months
  • 500 — 100,000 SHU

Different plant families (Rosaceae, Cucurbitaceae, Asteraceae). The full vanillylamine branch and condensation step must be introduced heterologously. Multi-gene stacking (8-10 cassettes on T-DNA) and synthetic biology are required.

T4

Frontier

Full Synthetic Pathway

  • 10-12 heterologous genes
  • <30% synteny
  • 48-72 months
  • 100 — 10,000 SHU

Evolutionarily distant from Capsicum, with fundamentally different secondary metabolism and severe transformation challenges. The complete capsaicinoid pathway must be installed as a synthetic gene cluster — long-term research targets.

Master catalog

All 57 products.

SKUNameOrganismTierTarget SHU
SS-TOM-01EmberTomatoT15K
SS-TOM-02MagmaTomatoT150K
SS-TOM-03PyroclastTomatoT1250K
SS-TOM-04CalderaTomatoT1500K
SS-TOM-05KrakatoaTomatoT11M
SS-EGG-01SmolderEggplantT15K
SS-EGG-02NightshadeEggplantT150K
SS-EGG-03EclipseEggplantT1250K
SS-EGG-04ObsidianEggplantT1500K
SS-EGG-05Event HorizonEggplantT11M
SS-TOB-01Proof of ConceptTobaccoT110K
SS-TOB-02BenchmarkTobaccoT1100K
SS-TOB-03ThresholdTobaccoT1500K
SS-POT-01TremorPotatoT21K
SS-POT-02Fault LinePotatoT210K
SS-POT-03SeismicPotatoT250K
SS-POT-04TectonicPotatoT2200K
SS-POT-05RichterPotatoT2500K
SS-GCH-01SparkGround CherryT21K
SS-GCH-02FlareGround CherryT225K
SS-GCH-03SupernovaGround CherryT2100K
SS-TIL-01Green FuseTomatilloT21K
SS-TIL-02Verde VenomTomatilloT225K
SS-TIL-03Acid RainTomatilloT2100K
SS-PET-01Petal BurnPetuniaT210K
SS-PET-02Bloom BombPetuniaT2100K
SS-STR-01Warm KissStrawberryT3500
SS-STR-02Sugar BurnStrawberryT35K
SS-STR-03Candied FangStrawberryT325K
SS-STR-04Devil's DessertStrawberryT3100K
SS-CUC-01Cool BurnCucumberT3500
SS-CUC-02ParadoxCucumberT35K
SS-CUC-03ContradictionCucumberT350K
SS-MEL-01SunstrokeMelon & WatermelonT3500
SS-MEL-02HeatwaveMelon & WatermelonT35K
SS-MEL-03Solar FlareMelon & WatermelonT350K
SS-APL-01Forbidden BiteAppleT3500
SS-APL-02Serpent's GiftAppleT35K
SS-APL-03Original SinAppleT350K
SS-LET-01Sleeper AgentLettuceT3500
SS-LET-02Trojan LeafLettuceT35K
SS-LET-03Silent AlarmLettuceT350K
SS-CAR-01Core SampleCarrotT4100
SS-CAR-02Drill BitCarrotT41K
SS-CAR-03MantleCarrotT410K
SS-BRA-01CrucibleCabbage & CauliflowerT4100
SS-BRA-02Cold FusionCabbage & CauliflowerT41K
SS-BRA-03Chain ReactionCabbage & CauliflowerT410K
SS-BRC-01BrushfireBroccoliT4100
SS-BRC-02Crown FireBroccoliT41K
SS-BRC-03FirestormBroccoliT410K
SS-CRN-01StaticCornT4100
SS-CRN-02Lightning StrikeCornT41K
SS-CRN-03ThunderclapCornT410K
SS-RCE-01Ember GrainRiceT4100
SS-RCE-02Dragon's PortionRiceT41K
SS-RCE-03DynastyRiceT410K

Interest & licensing

Lock a Beyond Peppers organism before it ships.

Beyond Peppers specifications are complete; engineering is pending engineering deliverables. Early partners can reserve organism or sector licenses now.